Selank is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is derived from tuftsin, an immunomodulatory tetrapeptide naturally produced by the spleen, with an added Pro-Gly-Pro sequence designed to improve stability and resistance to enzymatic degradation.
Selank was developed by the same research team responsible for Semax, led by Nikolai Myasoedov. Since its introduction, Selank has been examined in a wide range of preclinical and clinical research involving neurobiology, stress response, and immune signaling.
The compound has become a notable area of study within neuroregulatory and anxiolytic peptide research due to its broad interaction with neurotransmitter and immune pathways.
Research suggests that Selank influences GABAergic neurotransmission and monoamine metabolism. Published studies have examined its effects on serotonin, dopamine, and norepinephrine balance within brain regions associated with stress adaptation and emotional regulation.
Additional research has explored Selank’s interaction with enkephalinase activity, IL-6 expression, and GABA receptor subunit signaling, suggesting a targeted influence on neurological and immune-related pathways.
Published research has explored Selank in models involving anxiety and stress response, immune modulation, neurotransmitter balance, inflammatory signaling, and cognitive performance under stress conditions.
Researchers continue to investigate Selank in broader neurobiological and CNS-focused studies involving adaptation, resilience, and regulatory signaling mechanisms.
Selank and Semax are frequently examined together in research due to their complementary mechanisms of action. While Semax is primarily associated with neurotrophic and cognitive signaling pathways, Selank has been studied for its influence on stress-response and immune-regulatory systems.
Together, the compounds are often explored within broader CNS-focused research models involving cognition, stress adaptation, and neurochemical regulation.
Selank should be stored at -20°C prior to reconstitution. Once prepared for research use, refrigerate at 2–8°C and avoid repeated freeze-thaw cycles to preserve peptide stability.
At White Label Research, Selank undergoes third-party HPLC and mass spectrometry testing to verify identity and purity. Certificates of analysis are available on the product page. Our standard threshold is ≥99% purity.
